The Hydragel LP A1 Particles assay is designed for the quantification of LP A1 particles in serum utilizing an electroimmunodiffusion technique. The initials LP followed by the apolipoprotein designation, such as LP A1, now designate particles containing lipids and one apolipoprotein. If more than one apolipoprotein is contained, they are noted in decreasing concentration separated by a colon as in LP A1:A2. Studies have shown that only LP A1 particles are involved in cholesterol efflux. Therefore any decrease in LP A1 constitutes an increase in atherosclerotic risk especially when associated with an elevation of Apo B.

Sebia's unique LP A1 Particle assay is designed such that an excess of anti-Apo A2 antibody is incorporated into the gel sufficient to block migration of all LP A1:A2 particles. Based on the principles of Laurel rocket electrophoresis, the result after staining is two superimposed rockets for each sample. The shorter, darker rocket corresponds to the blocked LP A1:A2 particles and is not measured. The higher rocket corresponds to the LP A1 particles and is measured with concentrations obtained when compared to the plotted standard curve.

Perfect for the research laboratory, Sebia's LP A1 assay is the kit many research scientists choose for its ease of use, clarity of results, fast processing, and excellent performance.