Hemoglobin electrophoresis

Hemoglobin electrophoresis is a test that is performed to measure the different types of hemoglobin in a person’s blood. It is performed when a doctor suspects that a patient has a genetic disease or disorder that stems from having abnormal hemoglobin, such as sickle cell anemia. In this form of electrophoresis, the hemoglobin particles are placed in an electric field.

There are four primary types of hemoglobin:

• Hemoglobin A, which is the major component of hemoglobin in an adult’s red blood cells
• Hemoglobin C, which is a hemoglobin variant primarily found in the black population that can cause hemolytic anemia
• Hemoglobin F, which is the major component of hemoglobin in a fetus but still exists in small quantities in adults
• Hemoglobin S, which is a hemoglobin variant primarily found in the black population that can cause sickle cell anemia

Sebia is a global leader in hemoglobin electrophoresis

Because of their varying electrical charges, when placed in this electric field, the hemoglobin particles will move and separate according to their specific types and form “bands.” A comparison of these bands to a normal blood sample will assist in diagnosing whether or not the person suffers from a disorder like sickle cell anemia.

The HYDRASYS^®, Sebia’s semi-automated instrument, test menu consists of alkaline and acid hemoglobin electrophoresis assays. To find out more about exciting advancements concerning totally automated hemoglobin electrophoresis testing via capillary electrophoresis, please contact us today.

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