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Immunotyping (IT), Sebia's patented alternative to immunofixation testing, is designed for the detection and characterization of monoclonal proteins in serum. All sample dilutions are completely automated; standard or nonstandard dilutions (for hypo- or hypergamma samples) are performed on the CAPILLARYS™ 2 system. Similar to agarose gel methodology, antisera is utilized; however, no antisera pipetting is required. A sealed, pre-prepared antisera cartridge is utilized.
Immunotyping is a completely automated assay from bar-coded primary sample tube to final result.
A small amount of sample (40 µL) is mixed with buffer and then added to each antisera well. A soluble immune complex is formed between the Ig and the corresponding antibody; no incubation, sedimentation or centrifugation is required.
The large antibody complex exhibits an altered or slowed anodic migration, moving outside of the determined detection window.
The untreated reference curve is compared to the immunological curves in order
to identify and type the
monoclonal component present in the sample.
View an introduction to Basic IT interpretation
http://www.brainshark.com/sebiaus/Immunotyping101
| P/N |
Description |
| 2100 |
CAPILLARYS™ Immunotyping (IT) |
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