|
An automated alternative to immunofixation testing
Designed for the detection and characterization of monoclonal proteins in serum utilizing
Sebia’s capillary electrophoresis (CE) instruments – CAPILLARYS 2 and MINICAP.
Immunotyping is a completely automated assay from bar-coded primary sample tube to the
final result report, offering true positive identification. Sample dilutions, standard or
nonstandard (hypogamma or hypergamma), are automatically performed by the instrument.
Similar to agarose gel electrophoresis, antisera is utilized; however, no manual antisera
pipetting is required. With CAPILLARYS 2, a sealed manufactured antisera cartridge is utilized.
With MINICAP, bar-coded antisera vials are placed directly on the carousel. Each serum sample
is mixed with individual antisera that are specific against gamma (IgG), alpha (IgA) and mu (IgM)
heavy chains, and kappa and lambda (free and bound) light chains.
View an introduction to
Immunotyping on CAPILLARYS 2
A small amount of sample is mixed with a specific diluent and is then mixed
with individual specific antisera. A soluble immune complex is formed rapidly between the Ig and the
corresponding antibody; no incubation, sedimentation or centrifugation is required. The large antibody
complex exhibits an altered or slowed anodic migration, moving outside of the determined detection window.
The untreated reference curve is compared to all of the immunological curves in order to
identify and type the
monoclonal component present in the sample.
| P/N |
Description |
| 2100 |
CAPILLARYS Immunotyping |
| 2003 |
CAPILLARYS Protein 6 |
| 2300 |
MINICAP Immunotyping |
| 2223 |
MINICAP Protein 6 |
|
