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CAPILLARYS™ Hemoglobin -
Aid in the diagnosis of hemoglobinopathies and thalassemia

View an introduction to CAPILLARYS Hemoglobin technology

The CAPILLARYS Hemoglobin assay is designed to separate, detect, and quantify normal hemoglobins and hemoglobin variants. This assay has been adapted to the Sebia capillary electrophoresis system, CAPILLARYS 2, in order to provide complete automation. Direct analysis is performed from the bar-coded, primary tube on packed, unwashed red blood cells. Red cell hemolysate is automatically prepared on the instrument; sample migration occurs; and relative quantification & presumptive identification of the hemoglobin fractions take place all with a throughput of 34 samples per hour. Multiple capillaries functioning in parallel, yet independently, allow seven simultaneous analyses and are the primary reason for the CAPILLARYS’ high-throughput.

The CAPILLARYS Hemoglobin assay via capillary electrophoresis provides the following:

  • Complete automation from hemolysate preparation to relative quantification & presumptive identification of hemoglobin fractions
  • Minimal sample requirement, as is the nature of capillary electrophoresis technology
  • Positive ID with bar-coded, primary tube sampling
  • Easy-to-interpret, clean result curves without extraneous peaks
  • Enhanced resolution and focalization in the separation of variants and accurate quantification of Hb A2, F, and S with impressive correlation with HPLC
  • Separation of Hb E from the A2 fraction, facilitating identification and quantification
  • Clearly detectable and identifiable Hb H and Bart’s, as seen in alpha-thalassemia
  • Stored Hb AFSC Control reference curve overlay, facilitating variant ID such as closely migrating Hb S from Hb D and G

    P/N Description
    2007 CAPILLARYS™ Hemoglobin Kit
    4778 Normal Hb A2 Control/ Migration control
    4779 Pathological Hb A2 Control
    4791/4792 Hb AFSC Control
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