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Aid in the diagnosis of hemoglobinopathies and thalassemia
View an introduction to CAPILLARYS Hemoglobin technology
The CAPILLARYS Hemoglobin assay is designed to separate, detect, and quantify normal hemoglobins
and hemoglobin variants. This assay has been adapted to the Sebia capillary electrophoresis system,
CAPILLARYS 2, in order to provide complete automation. Direct analysis is performed from the bar-coded,
primary tube on packed, unwashed red blood cells. Red cell hemolysate is automatically prepared on the
instrument; sample migration occurs; and relative quantification & presumptive identification of the
hemoglobin fractions take place all with a throughput of 34 samples per hour. Multiple capillaries functioning
in parallel, yet independently, allow seven simultaneous analyses and are the primary reason for the CAPILLARYS’
high-throughput.
The CAPILLARYS Hemoglobin assay via capillary electrophoresis provides the following:
Complete automation from hemolysate preparation to relative quantification & presumptive identification of hemoglobin fractions
Minimal sample requirement, as is the nature of capillary electrophoresis technology
Positive ID with bar-coded, primary tube sampling
Easy-to-interpret, clean result curves without extraneous peaks
Enhanced resolution and focalization in the separation of variants and accurate quantification of Hb A2, F, and S with impressive correlation with HPLC
Separation of Hb E from the A2 fraction, facilitating identification and quantification
Clearly detectable and identifiable Hb H and Bart’s, as seen in alpha-thalassemia
Stored Hb AFSC Control reference curve overlay, facilitating variant ID such as closely migrating Hb S from Hb D and G
| P/N |
Description |
| 2007 |
CAPILLARYS™ Hemoglobin Kit |
| 4778 |
Normal Hb A2 Control/ Migration control |
| 4779 |
Pathological Hb A2 Control |
| 4791/4792 |
Hb AFSC Control |
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