Carbohydrate-deficient Transferrin (CDT): A chronic alcohol abuse marker. The CAPILLARYS™ CDT assay is designed for the separation of serum transferrin isoforms in alkaline buffer. Utilizing the CAPILLARYS™ 2, Sebia's completely automated capillary electrophoresis instrument, normal serum transferrin isoforms separate into five major fractions according to their sialylation level — asialotransferrin, disialotransferrin, trisialotransferrin, tetrasialotransferrin and pentasialotransferrin. The low-sialylated isoforms form CDT, which is indicative of chronic alcohol abuse. CDT is an up–and–coming assay with many exciting diagnostic areas such as alcohol rehabilitation profiles, employee testing, neurology panels and prenatal panels just to name a few.

CAPILLARYS™ CDT is a completely automated assay from bar-coded primary sample tube to final result with a throughput of 38 samples per hour.

Learn more about the history of CDT and how previous methods compare to the newest technology - Sebia’s completely automated CDT assay. Read the published article, “But he only has one drink before dinner”, featured on www.LifeUnderwriting.com or download the PDF version. Within the article, Dr. Pamela Bean describes the advantages of the CAPILLARYS™ CDT assay and features quotes from renowned contacts in the life insurance industry concerning the CAPILLARYS™ CDT assay.