|
Bence Jones is another innovative Sebia product. This assay is designed to type, with only one test, any monoclonal proteins found in urine samples. This assay is unique in that unconcentrated urine is used eliminating the cost and time involved in concentrating fluids. The Bence Jones test is an immunofixation assay which is processed virtually identically to Sebia's other IF assays with antisera being applied after the sample is electrophoresedutilizing the labor saving Dynamic Mask. The Bence Jones antisera kit contains five antisera: a trivalent consisting of IgG, IgA, and IgM, two antisera detecting both free and bound Kappa and Lambda Light Chains, and two antisera detecting only free Kappa and Lambda Light Chains. This unique combination of antisera allows the positive identification of true free light chain, or Bence Jones, proteins ruling out, with confidence, the possible presence of IgD or IgE.
The enhanced sensitivity of the assay, in part achieved by using an acid violet stain, combined with unsurpassed band resolution and gel clarity facilitates interpretation. Gels and kits are available in a range of sizes to accommodate any size workload while providing optimal cost effectiveness for all laboratories.
|