Abnormal bands in electrophoretic patterns, primarily those in the beta-globulins and gamma-globulins zones, are always suspect for being monoclonal proteins and therefore an indication of gammopathies. To identify these abnormal bands, the technique of immunofixation is applied.

Sebia’s Bence Jones assay is designed for qualitative detection and identification of Bence Jones proteins, monoclonal kappa and/or lambda free light chains, in human urine or serum, by immunofixation electrophoresis. The detection of Bence Jones proteins serves as a qualitative aid in the identification of monoclonal gammopathies.

This assay is unique in that unconcentrated urine can be used, eliminating the cost and time involved in concentrating fluids. The Bence Jones antisera kit contains five antisera: a trivalent consisting of IgG, IgA, and IgM, two antisera detecting both free and bound Kappa and Lambda Light Chains, and two antisera detecting only free Kappa and Lambda Light Chains.

Gels and kits are available in a range of sizes to accommodate any size workload while providing optimal cost effectiveness for all laboratories.