1.	Alkaline Phosphatase Isoenzymes Simply stated, alkaline phosphatase is an enzyme that helps cells function. Within this presentation, explore the physiological functions of alkaline phosphatase isoenzymes, as well as the normal and pathological occurrences and conditions which may result in increased of various fractions – bone, liver, placenta, and intestinal. A description of Sebia’s innovative approach to alkaline phosphatase isoenzyme measurement is presented in a clinical case study format.
2.	Alpha-1-Antitrypsin (A1AT) Deficiency and Phenotyping A1AT deficiency is one of the most common serious hereditary disorders in the world and can result in life-threatening lung or liver disease in children and adults. In fact, A1AT deficiency is the most common genetic cause of liver disease in children. Within this presentation, learn about the potential clinical presentation of A1AT deficiency, the prevalence of this hereditary disorder, potential screening methodologies, various A1AT phenotypes, as well as methods for the determination of A1AT Phenotypes.
3.	Cerebrospinal Fluid (CSF) Proteins, the Study of CSF is a clear body fluid that flows around the brain and spinal cord in order to surround and protect them. CSF is continually produced, circulated, and absorbed into the blood. Approximately 500 mL of CSF is produced daily, meaning that all of the CSF is replaced every few hours! Testing a sample of CSF can be invaluable in diagnosing a variety of conditions affecting the central nervous system. Within this presentation, explore the physiological variations in cerebrospinal fluid proteins and multiple methods of study, including clinical case studies.
4.	Hemoglobinopathy and Thalassemia Testing utilizing Capillary Electrophoresis (CE) Technology The Sebia CAPILLARYS Hemoglobin assay, utilizing capillary electrophoresis technology, provides a high-resolution separation of hemoglobins in order to detect and quantify normal and variant hemoglobins in one analysis. Within this presentation, discover the fundamentals of hemoglobinopathies and thalassemias; the importance of an accurate Hb A2 value as an aid in the diagnosis of thalassemias; a comparison of capillary electrophoresis technology to other current methods such as alkaline & acid hemoglobin gel electrophoresis, isoelectric focusing (IEF), and high-performance liquid chromatography (HPLC).
5.	Principles of Capillary Electrophoresis (CE) Technology and Electroosmotic Flow (EOF) Sebia’s CAPILLARYS 2 and MINICAP instruments utilize innovative capillary electrophoresis (CE) technology, an alternative to traditional agarose gel electrophoresis. Within this presentation, discover the science and principles behind CE technology and EOF. Answer the question “what’s happening inside the capillary?”